Marijuana is the most commonly used psychotropic drug in the United States, after alcohol. With the legalization and decriminalization of cannabis, momentum continues to build and propelled by the reduction of stigma associated to its consumption, there is growing concern regarding the long-term impact on brain function and behavior. Cannabis and the Developing Brain aims to provide comprehensive research on the effects of cannabis during neurodevelopment stages (i.e., perinatal and adolescent ages). This book introduces readers to vivo neural circuits, molecular and cellular mechanisms affected by cannabis exposure during three different temporal windows of brain vulnerability. Second, it offers a unique insight to shared neurobiological features of cannabinoid exposure during different developmental periods. Lastly, Cannabis and the Developing Brain determines the adverse impact of developmental cannabinoid exposure on specific cognition, emotion and behaviors.
Miriam Melis is an Associate Professor at the University of Cagliari, Italy. She holds a PharmD (University of Palermo, 1993) as well as a PhD in Neuroscience (University of Cagliari, 2011). During her career she worked as a Research Fellow for two years at the Ernest Gallo Clinic and Research Center at UCSF and as a Visiting Scientist at Lund Universitet Wallenberg Neuroscience Center in 2011. Her research is focused on understanding neurobiological mechanisms (i.e., adaptations of both mesocorticolimbic dopamine and endocannabinoid signaling) of resilience and susceptibility to adverse neurodevelopmental outcomes leading to neuropsychiatric disorders (e.g., psychotic- spectrum, substance use disorder, antisocial behavior, anxiety, depression). She has published 46 research papers, 5 book chapters and edited two books specifically on the effects of (endo)cannabinoids in the CNS. Olivier Manzoni is Research Director at the Mediterranean Neurobiology Institute, INSERM, in Marseille, France. He holds a PhD in Neuroscience (University of Montpellier, 1992). During his career he was a post-doctoral fellow at the University of California San Francisco and the Vollum Institute in Portland, Oregon and a Visiting Scientist at Cagliari University in 2018. Using animal models of both sexes, his research focuses on understanding how meso-corticolimbic microcircuits are shaped throughout early-life critical periods, to give rise to harmonious emotional behaviors and cognitive functions in adulthood. The overarching goal is to clarify how environmental and genetic insults modelling neuropsychiatric diseases, transform the architecture and the functionality of synaptic networks and thereby reduce the behavioral working range. He has published over 100 research papers.
Title: Cannabis and the Developing Brain
Author:
ISBN: 9780128234907
Binding:
Publisher: Elsevier Science Publishing Co Inc
Publication Date: 2022-08-18
Number of Pages: 360
Weight: 0.4492 kg